Workpackage 5 : Allogeneic use of mesenchymal stem cells MSC: detection of immunological response raised by allogeneic MSC transplantation; understanding of host response and mode of action 

 

Objectives :

 

• To identify molecular mechanisms associated with the immunosuppressive capacity of human MSCs in Degenerative Discopathy (DDD).

• To propose a potency test associated with MSCs modulation. 

• To test NP differentiation of MSC as a putative potency assay.

 

3 partners participate to the fifth workpackage : the CHUM,  the NUIG and the CNRS.