Workpackage 5 : Allogeneic use of mesenchymal stem cells MSC: detection of immunological response raised by allogeneic MSC transplantation; understanding of host response and mode of action
• To identify molecular mechanisms associated with the immunosuppressive capacity of human MSCs in Degenerative Discopathy (DDD).
• To propose a potency test associated with MSCs modulation.
• To test NP differentiation of MSC as a putative potency assay.
3 partners participate to the fifth workpackage : the CHUM, the NUIG and the CNRS.